Things you might not know about GLP-1 medications…
In our current thin-is-in-again diet culture climate, talk of GLP-1’s is everyyyywhere. And because I frequently get asked about them, I thought it’d be helpful to address a few facts about GLP-1 medications.
Firstly, GLP-1 receptor agonists are medications that mimic the hormone glucagon-like peptide-1 (GLP-1), which is naturally released in the gut after eating.
GLP-1 medications work by:
increasing feelings of fullness
slowing gastric emptying
reducing appetite and food noise, and
improving blood sugar regulation
In short, GLP-1 meds make it easier to eat less by changing hunger and satiety,
not by “burning fat” or speeding up metabolism.
GLP-1 medications are primarily indicated for:
people with obesity (BMI ≥30) or
people with a BMI ≥27 with weight-related conditions such as:
+ type 2 diabetes
+ insulin resistance
+ cardiovascular risk factors
GLP-1 medications are not designed as a cosmetic weight-loss tool or a first-line intervention for people without metabolic risk and/or who have not employed dietary and lifestyle interventions.
GLP-1s medications are intended for long-term use
Similar to medications for blood pressure or diabetes, continued use = continued results.
Research consistently shows appetite and hunger signaling return when medication is discontinued,
with a significant portion of lost weight being regained - especially without strong habit support.
GLP-1 medications can produce great short-term weight loss, HOWEVER:
lifestyle habits still determine health outcomes, and
long-term success still depends on behavior, support, and sustainability
The bottom line: GLP-1s lower the barrier to weight loss by reducing biological resistance, but long-term outcomes still depend on how someone eats, moves, and supports their body in conjunction with medication support.
GLP-1s can be a powerful tool for appetite regulation and metabolic support, life-changing for the right population, and work most effectively when combined with nutrition coaching.